Determination of serum interleukin 33 (IL-33) levels in atopic asthma patients using ELISA kits
نویسندگان
چکیده
منابع مشابه
Interleukin (IL)-33: new therapeutic target for atopic diseases.
Interleukin (IL)-33, a member of the IL-1 family of cytokines, is produced when epithelial and endothelial cells are exposed to stimuli. Hematopoietic cells such as macrophages also produce IL-33. IL-33 is considered to function as an 'alarmin', activating various immune cells through its receptor ST2, which leads to the production of various molecules. The IL-33-induced production of pro-infla...
متن کاملMeasurement of Interleukin-33 (IL-33) and IL-33 Receptors (sST2 and ST2L) in Patients with Rheumatoid Arthritis
The interleukin-33 (IL-33)/ST2 pathway has emerged as an intercellular signaling system that participates in antigen-allergen response, autoimmunity and fibrosis. It has been suggested that IL-33/ST2 signaling has been involved in the pathogenesis of rheumatoid arthritis (RA), because IL-33 and its receptor have been specifically mapped to RA synovium. The aim of this study was to determine the...
متن کاملIL-25 and IL-33 Serum Levels are not Associated with the Type of Allergen Causing Allergic Rhinitis
Background: Fungal aeroallergens might sensitize the airway which in turn produces a specific cytokine profile. Objective: To evaluate the IL-25 and IL-33 profile in patients with fungal allergic rhinitis. Methods: The present study examined patients who were evaluated due to allergic rhinitis (AR) at Emam Reza Hospital of Shiraz, Iran. The all...
متن کاملserum levels of interleukin-27 and interleukin-33 in patients with dermatomyositis and polymyositis compared to healthy control subjects
background in some autoimmune diseases such as rheumatoid arthritis (ra), interleukin-27 (il-27) and il-33 levels are increased. these observations suggest that il-27 and il-33 may have a role in the pathogenesis of polymyositis/dermatomyositis (pm/dm). conclusions these data indicate that il-27 might be selectively involved in the pathogenesis of dm and pm. however, il-33 does not appear to be...
متن کاملMeasuring serum concentrations of interleukin-33 in atopic dermatitis is associated with potential false positive results.
BACKGROUND In the search for valid biomarkers in inflammatory diseases, cytokine serum concentrations are often measured by enzyme-linked immunosorbent assay and correlated to disease activity. Interleukin-33 is a relatively newly described cytokine, which holds a promising potential as a biomarker for different diseases including atopic dermatitis. However, interfering human anti-animal IgG an...
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ژورنال
عنوان ژورنال: Journal of Fundamental and Applied Sciences
سال: 2018
ISSN: 1112-9867
DOI: 10.4314/jfas.v9i6s.69